Post-doc / Engineer, in vitro and in vivo preclinical… | Linksium
Recherche de salarié(e) d'un projet

Post-doc / Engineer, in vitro and in vivo preclinical tests for electrophysiology recording and stimulation via an innovative medical device.

Group Created with Sketch.
Postuler à cette opportunité

Description du projet

BrainTech Lab is a translational technological research unit dedicated to the development of innovative neurotechnologies for brain diseases. The Lab addresses biomedical needs related to brain tumors, neurodegenerative diseases, or disabilities.

This post-doc mission will contribute to the validation of the proof-of concept for a new medical device (MD) ‘Neuro Snooper’ in preclinical models (animal/in vitro), a required step before initiating a clinical trial (Technology Readiness Level from 2/3 to 4). Already existing MDs with electrode wires are either very stiff or with a milli-metric dimension. The ERC work has led to a first generic, miniaturized prototype implant with moderate invasiveness and which design was validated in connection with neurosurgeons. It is in particular suitable for the glioblastoma (GBM) application. In a long-term perspective, it will help to characterize brain signals and hyperexcitability in several brain diseases.

Description de l'offre

Missions

- Perform cell characterization around the future medical device: impedance measurement, electrophysiology recording/ stimulation (in vivo/in vitro), signal analysis, immuno-cyto/histo-chemistry, microscopy

- Keep appropriate experimental records and documentation and present the results analysis to the Principal Investigator

- Keep a notebook for the characterization of each medical device

- Participate to animal experimentation and to in vitro cell culture

- Participate to the micro-nanofabrication in clean-room

- Participate to the redaction of publications

Description du profil

Scientific and technical competences

- Electrophysiology (in vitro cells/tissues and/or in vivo)

- Signal analysis (spike sorting, local field potentials, correlations and fourrier analysis)

- Immune-cyto/histo-chemistry

- Cell culture is a plus (cell line, primary cells)

- Habilitation for animal experimentation (not mandatory but it is a plus)

- Neuroscience, electrochemistry or electronics for neuro-recording

 

Soft skills

- Communication skills for a successful interaction with the research team and in particular with the medical/ preclinical staff.

- Ability to learn new techniques, in particular cell culture/ micro-fabrication (clean-room work: optical lithography, material etching and deposition, etc).

- Meticulous work for the reproducibility of biological and technological process

- High motivation for medical research

Remuneration

The salary will be adjusted based on qualifications and experience.

Contact

Candidate should send a CV and a motivation letter to gaelle.offranc-piret@inserm.fr

À propos de Linksium

Linksium, Société d’Accélération du Transfert de Technologies du sillon alpin, accompagne depuis le laboratoire la création de startups deeptech en mobilisant son équipe pluridisciplinaire, ses experts sectoriels, son programme de formations et des leviers de financement. Linksium est aussi co-fondateur des startups accompagnées. Plus de 70 startups ont été co-fondées à ce jour dans les domaines Santé, Numérique, Energie & Environnement, Matériaux et Procédés, Sciences Humaines et Sociales.

Postuler à cette opportunité

Nos startups et projets recrutent

Aec48fe0 c870 4334 a10a 065165da96af cd38b6ec ddd5 43b2 b61a 70e44c0caf36
CEO Associé(e) Start-up « NANOTIP » - Nano caractérisation thermique en microélectronique

En tant que CEO vos missions à court terme consisteront àVous construisez l’offre sur les marchés à fort potentiel en partenariat avec les clients pionniers déjà identifiés et vous enrichissez le p...

8f5705b6 e808 484b a112 b84010c56686 2be98d69 add2 4b77 83bf 89b2c1ba3f60
Ingénieur en Robotique H/F

La mission consiste à prendre en main la base rover du démonstrateur, comprendre ses interfaces, l’équiper des différents capteurs (intégration mécanique et électronique), et contribuer à l’impléme...

8f5705b6 e808 484b a112 b84010c56686 2be98d69 add2 4b77 83bf 89b2c1ba3f60
Ingénieur DevOps H/F

Nous recherchons un développeur logiciel talentueux et passionné pour rejoindre notre équipe. Le candidat retenu sera chargé dans un premier temps de construire une usine logicielle qui nous permet...