THE ELEMENT
Implantable device for chronic hydrogen therapy against Parkinson's disease
Benefits
- Neuroprotective treatment
- Low invasiveness
- Chronic treatment
Key words
- Parkinson's disease
- Hydrogen therapy
- Implantable device
Intellectual Property
- 1 patent
Partnerships & Rewards
- Région Auvergne-Rhône-Alpes
- 2023 French Deeptech Innovation Competition Winner
Laboratory
- TIMC-IMAG
Institutions
- CNRS
- GRENOBLE INP-UGA
- UGA
Linksium Continuum
- Maturation
- Incubation
Results
- Incorporated startups
Context
Ten million people worldwide have Parkinson's disease. This number will increase by 56% by 2030. On the one hand, the symptoms of Parkinson's disease can be treated, but on the other hand, there is no therapy to slow down the neuronal degeneration associated with the disease.
Technology
The ELEMENT develops an implantable device named HOPE "Hydrogen Operating Parkinson Elimination". HOPE is able to provide chronic hydrogen therapy. Hydrogen is a strong and selective antioxidant. It can slow down neuronal degeneration.
Advantages
- A chronic treatment: no patient involvement for five years
- A stable dose of hydrogen over several years
- Minimally invasive: outpatient surgery for device implantation
- Reduction of healthcare costs
State of progress
A first version of the HOPE device has been developed and a conclusive preclinical study on a parkinsonian rat model has been performed. The neuro-protective effect of hydrogen has been validated.
Applications
The active implantable medical device developed by the future startup THE ELEMENT targets applications in the field of neurodegenerative diseases.
