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Formulation of microsystems based on bio-modified cyclodextrin derivatives

profilePhoto   Gisela Schach
Linksium Contact Gisela Schach +33 (0)6 33 63 44 99


  • Biosourced and biocompatible
  • Controlled release
  • Slow release
  • Prolonged stability

Key words

  • Cyclodextrins
  • Active ingredients
  • Encapsulation
  • Personal care

Intellectual Property

  • 1 knowhow


  • DPM


  • CNRS
  • UGA

Linksium Continuum

  • Maturation


Active ingredients are highly oxidative substances that degrade rapidly and constantly react with the environment and other cosmetic ingredients. By encapsulating them, we ensure the stability of cosmetic actives and protect them from possible reactions with the formulation or the environment.


Cyclo-ARTESS has developed an innovative process allowing the encapsulation of a range of active substances with a protective layer composed of bio-esterified cyclodextrin derivatives due to their self-organization in an aqueous medium. The micro-encapsulation consists of a core of liquid or solid active material protected by a layer or matrix of cyclodextrins.


Some of the advantages of this innovative encapsulation process are:

  • high efficiency of the encapsulation
  • controlled release of the active ingredients
  • maximum protection of the active ingredient against oxidation, light, temperature, hygroscopy or interaction with other components
  • high content of the active ingredient
  • granulometry between 0.2 and 0.5 µm.

The product complies with the COSMOS (Bio) specifications and a strict charter of sustainable development.

State of progress

Proof of concept under validation. Example of microencapsulated actives: vitamins and cosmetic actives.


Main application is a use in natural and organic personal care products.

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